Curriculum Vitae - Stephen P. Holland, M.D.
Work Address:

Stephen Holland, MD, FACP
Chief, Division of Gastroenterlogy
Mt. Sinai Hospital, Department of Internal Medicine
1501 S. Fairfield
Chicago, IL  60608
773-542-2000
eMail: stephen.holland@sinai.org

Birth date: 1-8-58, Chicago, Illinois

Education:

Undergraduate:  Northwestern University    BS    9/1976-6/1980
        Honors Program in Medical Education
Medical School: Northwestern University    MD    9/1978-6/1982
Residency:      Loyola University, Internal Medicine, 7/1982-6/1985
Fellowship:     NRSA Immunology trainee,University of Alabama, 7/1985-6/1988, 
        with Dr. Jerry McGhee.
Fellowship:     Gastroenterology, University of Alabama, 7/1988-6/1991

Licensure and Certification:

Licensed Physician and Surgeon, Illinois  036-068571
Board Certified Internal Medicine #102384 9/11/85
Board Certified Gastroenterology #102384 11/5/91

Honors and Awards:

Winner, Radiology Case of the Week, Department of Radiology, 
        U of Illinois College of Medicine at Peoria 
        (UICOM-P) - 1997, 1998, 1999
Invited Teaching Attending, Department of Internal Medicine,
        U of Illinois College of Medicine at Peoria 
        (UICOM-UC), 1996, 1997, 1998
Internal Medicine Teacher of the year, UICOM-UC, 2000


Positions and Grant Support:

7/1991-12/1993 NRSA Awardee, NIADDK 1F32 DK08633-01A1, University of Alabama at Birmingham.

1/1994-9/1995 Attending Physician, Hoover Family Medicine; 1575 Montgomery Highway; Hoover, AL 35216

1/1994-9/1995 Attending Physician, MedHelp; Suite 100; 1 Lakeshore Drive; Birmingham, AL 35209.

10/1995-10/1997 Assistant Professor Clinical Pharmacology, Universityof Illinois College of Medicine at Peoria.

10/1995-5/1999 Clinical Assistant Professor of Medicine, University of Illinois College of Medicine at Peoria.

10/1995-5/1999 Attending Physician, Gastroenterology, Ltd.; 900 Main Street - Suite 530; Peoria, IL 61602.

10/1997-7/1999 Adjunct Assistant Professor Clinical Pharmacology, University of Illinois College of Medicine at Peoria.

7/1999-11/1999 Attending, Peoria Outpatient Clinic, Veterans Administration, Peoria, Illinois.

12/1999-1/2002 Attending Physician, Gastroenterology; Christie Clinic, Champaign, IL.

1/2002-10/2002    Attending Physician, Gastroenterology Consultants; 545 Valley View Drive; Moline, IL  61265; 309-762-0529

10/2002-4/2014    Attending Physician, Naperville Gastroenterology; 636 Raymond Drive, Suite 201; Naperville, IL  60563; 630-357-4463

4/2014-present     Chief of Gastroenterology, Mt. Sinai Medical Group; 1501 S. Fairfield; Chicago, IL  60608; 773-542-2000



Education - Courses Taught and Student Projects:

Clinical Trial Design, University of Illinois College of Medicine at Peoria (UICOM-P) Clinical Pharmacology Program - 1997.

Normal Gut Flora, Medical Microbiology, UICOM-P - 1996,1997,1998,1999

Gastrointestinal Pharmacology, UICOM-P - 1996, 1997, 1998, 1999

Pancreas and UGI Hormones, Gastrointestinal Organ Systems, UICOM-P - 1996,1997

Irritable Bowel Syndrome and Inflammatory Bowel Disease, Gastrointestinal Organ Systems, UICOM-P - 1996, 1997

Inflammatory Bowel Disease, Gastrointestinal Organ Systems, UICOM-P -1998, 1999

Student Advisor, John Densmore, Betaine in Alcoholic Hepatitis, 6/1997 - 10/1997

Student Advisor, Shawn Seibert, James Scholar Project, S. mutans in Crohn's Disease, 6/1997-8/1997

Inflammatory Bowel Disease Case Presentations - UICOM/P Internal Medicine Residency Seminar Series - 12/23/97

Gastroenterology Teaching Seminar, UICOM/UC (Urbana/Champaign) Internal Medicine Residency Seminar Series - 12/99 to 2001

Gastrointestinal Pharmacology, UICOM-UC - 2000, 2001

Clinical Faculty, Avalon University School of Medicine - 2012 - 2014

Clinical Faculty, University of Medicine and Health Sciences - 2012 - 2014

Clinical Faculty, Ross University School of Medicine - 2016 - present



Education - Seminars:

Clinical Implications of Research in Inflammatory Bowel Disease - Society of Gastrointestinal Nursing Assistants - 4/97

Betaine in Alcoholic Liver Disease, Invited Speaker, GI Grand Rounds, Uof I College of Medicine at Chicago - 2/25/98

NSAID's and the GI tract - CME seminar sponsored by Pfizer/Searle - Peoria 3/6/99

COX-2 Inhibitors and the GI tract - CME seminar sponsored by Pfizer/Searle - Springfield 3/25/99

Screening Strategies for colorectal Cancer - CME seminar Family Practice - Champaign 2/2000



Committees:

Pharmacology and Therapeutics Committee, St. Francis Hospital, University of Illinois College of Medicine at Peoria. 1995-1999

Chairman, Enteral and Parenteral Nutrition subcommittee, Pharmacology andTherapeutics Committee, St. Francis Hospital, University of Illinois Collegeof Medicine at Peoria. 1995-1999

Steering Committee, Gastroenterology Section, Organ Systems Course, UICOM-P. 1998

Pharmacology and Therapeutics Committee, Methodist Hospital,1998-1998

Pharmacology and Therapeutics Committee, Provena Covenant Hospital, 1998-1999

Pharmacology and Therapeutics Committee, Adventist Bolingbrook Hospital, 2008-2014



Professional and Society Membership:

American College of Physicians, 1983 - .

Crohn's and Colitis Foundation of America, 1992 - .

American Gastroenterological Association, 1995 - .

American Medical Association, 1995 - .



Intramural Presentations:

New Issues in Gastroenterology - H. pylori and Proton Pump inhibitors - U of I Family Practice Grand Rounds 2/16/96.

Clinical Applications of Research in Inflammatory Bowel Disease - Internal Medicine Grand Rounds - UICOM/P - 5/6/97



Research Interests:

Inflammatory Bowel Disease, Bacterial-host interaction.

Alcoholic Liver Disease, Betaine in modification of disease.

Nutrition in Fatty Liver, Irritable Bowel Syndrome, and other GI diseases.



Patents:

Method of Diagnosing Crohn's Disease. US Patent 6,235,487.

Method and Apparatus for Treating Refractive Eye Abnormalities. US Patent 5,838,419.



Community Activities:

Host of two sites for education of patients through the internet:

Web site: The IBD Page <http://www.ibdpage.com/>; also host of IBD section of WebMD through 6/2001

Contributor to the IBDList, an IBD related list serve.

Volunteer, American Red Cross;

Lecture: Irritable Bowel Syndrome, Springer Cultural Center, 2/1/2001

Inflamatory Bowel Disease Expert, WebMD <http://www.WebMD.com/>, 10/1999 - 7/2001



Bibliography:

Holland S, David RJ. An outcome-coded birth file from machine readable vital records. Comput-Biol-Med. 1985. 15(1):25-39.

Holland SP, Eldridge J, Alley CD, McGhee JR. Immunoglobulin A Secretion. In: Handbook of Physiology. The Gastrointestinal System. IV. Absorbtive and Secretory Processes of the Intestines. Frizzell R, ed. Am. Physiol. Soc. 1990.

Holland SP, Kiyono H, Michalek SM, McGhee JR. Gut immunology: Characterization of rat lamina propria lymphocytes. Federation Proceedings (Abstract) 46(3):473, 1987.

Holland SP, Go MF, Hirshowitz BI, and Michalek SM. Antibody response to Campylobacter Pylori in peptic ulcer disease. Abstract, American Society of Microbiology, Miami Beach, FL. 1988.

Holland SP, Go MF, McGhee JR, and Hirshowitz BI. Immunobiology of Campylobacter pylori: Antigenic variation among isolates. Campylobacter pylori workshop. Keystone CO 1988.

Berstad A, Alexander B, Weberg R, Serck-Hanssen A, Holland S, and Hirshowitz BI. Antacids reduce campylobacter pylori colonization without healing the gastritis in patients with nonulcer dyspepsia and erosive prepyloric changes. Gastroenterology 95:619-24, 1988.

Elson CO, Holland S, Woogen S. Preferential inhibition of the CD8+ T cell subset by Cholera Toxin and its B Subunit. Abstract, American Association of Immunology. FASEB J. 4:A1864, 1990.

Holland, S. Bacterial and protozoal gastroenteritis [letter]. N-Engl-J-Med. 326(7):489 ,1992.

Holland S, Elson CO. Cholera toxin As an adjuvant: augmentation of a Th2 T cell response to parenteral antigen. Gastroenterology 144(4:2):A714,1993.

Holland, SP. Medical care delivery and factors affecting performance on a 150 mile bicycle tour. Clin J Sports Medicine, 3(4):242-50;1993.

Holland SP, Elson CO. Oral Tolerance in the Treatment of Autoimmunity. Practical Gastroenterology, 1993. 17(10):19-22, 1993.

Husby S, Mestecky J, Moldoveanu Z, Holland S, and Elson C. Oral Tolerance in Humans. T cell but not B cell tolerance after antigen feeding. Journal of Immunology 152(9):4663-70, 1994.

Elson CO, Holland SP, Dertzbaugh MT, Cuff CF, Anderson AO. Morphological and functional alterations of mucosal T cells by cholera toxin and its B subunit. (Submitted)

Holland SP, Brandwein SL, Elson CO. Sera from rats with peptidoglycan-polysaccharide enteritis demonstrates reactivity to proteins that are found in PG-PS preparations. Gastroenterology 146(4:2):2788, 1995.

Holland SP. Inflammatory Bowel Disease. In: Women's Medicine. ed: Blackwell, R.E. Blackwell Science, Cambridge Science 1996.

Holland SP, J. Densmore, N. Novotny, RN, Steven Belknap, MD. Safety of Betaine in Alcoholic Hepatitis. Gastroenterology 114(4:2):A1257, 1998.

Holland S. Serologic Response to Streptococcus Mutans in Crohn's Disease and Ulcerative Colitis. Gastroenterology 114(4:2):A997, 1998.

Holland S. It's all in the Water [letter]. Science News 155(24):371, 1999.